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Surface‐initiated atom‐transfer radical polymerization of 3‐ O ‐methacryloyl‐1,2:5,6‐di‐ O ‐isopropylidene‐α‐ D ‐glucofuranoside onto gold surface
Author(s) -
Yoon Kuk Ro,
Ramaraj B.,
Lee Seungho,
Yu JongSung,
Choi Insung S.
Publication year - 2008
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.31927
Subject(s) - atom transfer radical polymerization , materials science , contact angle , x ray photoelectron spectroscopy , polymer , polymer chemistry , radical polymerization , tetrahydrofuran , polymerization , chemical engineering , organic chemistry , chemistry , composite material , engineering , solvent
Abstract A sugar‐containing polymer was grown on gold surface by surface‐initiated atom‐transfer radical polymerization (SI‐ATRP) of methacrylate monomer, 3‐ O ‐methacryloyl‐1,2:5,6‐di‐ O ‐isopropylidene‐α‐ D ‐glucofuranoside (MAIpGIc), using 1,4,8,11‐tetraaza‐1,4,8,11‐tetramethylcyclotetradecane (Me 4 Cyclam) as ligand, 2‐bromopropionyl moiety attached on the gold surface as initiator, and Copper(I) bromide as catalyst, respectively, in tetrahydrofuran (THF) medium. The resultant sugar film was characterized by polarized infrared external reflectance spectroscopy (PIERS), X‐ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), field emission scanning electron microscopy (FE‐SEM), ellipsometry, and contact angle goniometry. The IR peaks characteristics of poly(3‐ O ‐methacryloyl‐α,β‐ D ‐glucopyranoside) (PMAGlc), broad OH stretch at ∼3400 cm −1 , and CO ester stretch at ∼1748 cm −1 observed in PIERS spectra demonstrate the formation of PMAGlc on the gold surface. The AFM and SEM images show the polymer growth away from the gold surface without visible domain boundaries, and it further confirms the formation of sugar coating. The method described in the article would be beneficial in many areas, such as pathogen detection and biosensors, considering the biological importance of carbohydrate polymers. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res, 2009