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Bioactive films on metallic surfaces for osteoconduction
Author(s) -
Zhang Qiyi,
Leng Yang,
Lu Xiong,
Xin Renlong,
Yang Xiudong,
Chen Jiyong
Publication year - 2009
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.31820
Subject(s) - materials science , titanium , octacalcium phosphate , simulated body fluid , metal , calcium , electrochemistry , amorphous calcium phosphate , deposition (geology) , amorphous solid , phosphate , metallurgy , chemical engineering , composite material , scanning electron microscope , electrode , paleontology , chemistry , organic chemistry , sediment , engineering , biology
A fast and effective electrochemical method was developed to make a dense calcium phosphate films on titanium and stainless steel for hard tissue replacement. The surfaces of titanium and stainless steel were cathodically treated in an electrochemical cell. By controlling the treatment parameters, a film of 100‐nm thickness was deposited on the metal surface in several minutes. The thin film was amorphous calcium phosphate containing octacalcium phosphate nuclei, and also dense and ductile. The treated metals were able to induce bioactive calcium phosphate deposition after immersion in simulated body fluid (SBF) for only 1 and 2 days. In vivo study was conducted by implanting the treated specimens of titanium and stainless steel in dog's femur cavity. The treated metallic surfaces showed good ability of osteoconduction. This surface treatment method can be potentially used to enhance bioactivity of any type of metallic surfaces. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res 2009