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The role of calcium gluconate in electrochemical activation of titanium for biomimetic coating of calcium phosphate
Author(s) -
Shibli S. M. A.,
Mathai Suja
Publication year - 2008
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.31809
Subject(s) - materials science , simulated body fluid , titanium , calcium , apatite , coating , chemical engineering , electrolyte , phosphate , layer (electronics) , surface modification , adhesive , metallurgy , composite material , chemistry , biochemistry , electrode , engineering
Supersaturation of calcium and phosphate in the bath solution and activation of the metal substrate is essential for effective biomimetic growth of apatite on orthopedic implants. In this work, bioactivation of titanium surface was achieved by electrodeposition of a thin layer of calcium phosphate followed by an alkaline treatment to obtain pure hydroxyapatite crystals. The influence of calcium gluconate in the electrolyte solution was evaluated and optimized. Adhesive strength, thickness, structural, and surface characteristics were evaluated. A highly adhesive and uniform layer of hydroxyapatite was formed on titanium surface when the electrodeposition was carried out with an electrolyte solution‐containing calcium gluconate. The electrodeposited hydroxyapatite coatings were subjected for biomimetic growth in Kokubo's simulated body fluid (SBF) and Kokubo's modified SBF containing 1.5 times higher concentration of Ca. Biomimetic growth was also improved by the addition of calcium gluconate in the SBF solution. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res 2008