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Vertical bone augmentation with granulated brushite cement set in glycolic acid
Author(s) -
Mariño F. Tamimi,
Torres J.,
Tresguerres I.,
Jerez L. Blanco,
Cabarcos E. López
Publication year - 2007
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.31014
Subject(s) - brushite , materials science , cement , calvaria , glycolic acid , bone cement , monocalcium phosphate , dental cement , ultimate tensile strength , resorption , composite material , nuclear chemistry , calcium , metallurgy , lactic acid , in vitro , chemistry , adhesive , bacteria , pathology , biology , genetics , biochemistry , layer (electronics) , fish <actinopterygii> , fish meal , medicine , fishery
Brushite cements are a biocompatible materials that are resorbed in vivo . A new cement composed of a mixture of monocalcium phosphate (MCP) and β‐tricalcium phosphate (β‐TCP) that sets using glycolic acid (GA) was synthesized and characterized. After setting, the cement composition, derived from X‐ray diffraction, was 83 wt % brushite and 17 wt % β‐TCP with an average brushite crystal size of about 2.6 ± 1.4 μm. The cement has a diametral tensile strength of 2.9 ± 0.7 MPa. Granules prepared from the set‐cement were used as grafting material in bone defects on rabbit calvaria for evaluating in vivo its bone regeneration capacity. Considerable cement resorption, improvement in the bone mineral density, and bone neoformation was observed after 4 weeks of the granules' implantation. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res, 2007