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Synthesis and temperature response analysis of magnetic‐hydrogel nanocomposites
Author(s) -
Frimpong Reynolds A.,
Fraser Stew,
Zach Hilt J.
Publication year - 2007
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.30962
Subject(s) - materials science , self healing hydrogels , ethylene glycol , nanocomposite , magnetic nanoparticles , nanoparticle , ethylene glycol dimethacrylate , chemical engineering , lower critical solution temperature , polymerization , microscale chemistry , composite number , monomer , radical polymerization , ethylene oxide , polymer chemistry , nanotechnology , polymer , composite material , copolymer , engineering , methacrylic acid , mathematics education , mathematics
Magnetically responsive hydrogel networks based on composites of magnetic nanoparticles and temperature responsive hydrogels were developed. These systems show great promise as active components of microscale and nanoscale devices and are expected to have a wide applicability in various biomedical applications. Specifically, nanocomposite hydrogel systems based on the temperature sensitive N ‐isopropylacrylamide hydrogels crosslinked with ethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate, and poly(ethylene glycol) 400 dimethacrylate (PEG400DMA) were synthesized and characterized. The composite systems were synthesized by UV free‐radical polymerization. Iron oxide magnetic nanoparticles were incorporated into the hydrogel systems by polymerizing mixtures of the nanoparticles and monomer solutions. The swelling response of these composite systems to different crosslinking molecular weights, temperature, and the effect of the presence of the magnetic nanoparticles were examined. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res, 2007