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Net expansion of dried demineralized dentin matrix produced by monomer/alcohol saturation and solvent evaporation
Author(s) -
Agee Kelli A.,
Becker Thomas D.,
Joyce Anthony P.,
Rueggeberg Frederick A.,
Borke James L.,
Waller Jennifer L.,
Tay Franklin R.,
Pashley David H.
Publication year - 2006
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.30752
Subject(s) - materials science , solvent , monomer , saturation (graph theory) , dentin , composite material , matrix (chemical analysis) , evaporation , chemical engineering , polymer , organic chemistry , thermodynamics , chemistry , engineering , physics , mathematics , combinatorics
The purpose of this work was to determine if nonaqueous methacrylate monomer/alcohol mixtures could expand dried collapsed demineralized dentin matrix. Thin disks (ca. 200 μm) of human dentin were demineralized and placed in wells beneath contact probes of linear variable differential transformers. The probes were placed on water‐saturated expanded matrices to record the shrinkage associated with drying. Monomer mixtures containing hydroxyethyl methacrylate, 2,2‐bis[4‐(2‐hydroxy‐3 methacryloyloxy)propoxyphenyl] propane, or triethyleneglycol dimethacrylate were mixed with methanol or ethanol at alcohol/monomer mass fraction % of 90/10, 70/30, 50/50, or 30/70. They were randomly applied to the dried matrices to determine the rate and magnitude of expansion; then shrinkage was recorded during evaporation of the alcohols. The results indicated that matrix expansion was positively correlated with the Hoy's solubility parameters for hydrogen bonding forces (δ h ) of the monomer/solvent mixtures ( p < 0.001). Expansions were more rapid with methanol‐containing than with ethanol‐containing monomer mixtures. For the test solutions, triethyleneglycol dimethacrylate‐containing mixtures produced the slowest rate of matrix expansion and hydroxyethyl methacrylate‐containing mixtures the most rapid expansion. When the solvents were evaporated, the matrix shrank in proportion to the solvent content and the δ h of the monomer‐solvent mixtures. The results indicate that expansion of dried, collapsed dentin matrices requires that the δ h of the mixtures be larger than 17 (J/cm 3 ) 1/2 . The greater the δ h of the monomer solutions, the greater the rate and extent of expansion. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res, 2006