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Biomaterials and scaffolds for ligament tissue engineering
Author(s) -
Ge Zigang,
Yang Fang,
Goh James C. H.,
Ramakrishna Seeram,
Lee Eng Hin
Publication year - 2006
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.30578
Subject(s) - materials science , tissue engineering , biomedical engineering , ligament , anatomy , engineering , medicine
Tissue engineering has achieved much progress in an attempt to improve and recover impaired functions of tissues and organs. Although many studies have been done, progress for tissue‐engineered anterior cruciate ligaments (ACLs) has been slow due to their complex structures and mechanical properties. In this review, the ACL anatomical structure, progresses achieved, material selection, structure design, and future direction have been discussed, while the challenges and requirements from materials and scaffolds are highlighted. There is a considerably huge amount work that needs to be carried out; as such, future direction in ligament tissue engineering is proposed in hope that this review will give information on future ligament tissue engineering. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res 2006