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Development of multifunctional polymer–mineral composite materials for bone tissue engineering
Author(s) -
Vlakh Evgenia G.,
Panarin Evgeniy F.,
Tennikova Tatiana B.,
Suck Kirstin,
Kasper Cornelia
Publication year - 2005
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.30428
Subject(s) - materials science , composite number , tissue engineering , adhesion , polymer , cell adhesion , biomedical engineering , cytotoxicity , chemical engineering , composite material , in vitro , chemistry , biochemistry , engineering
The main goal of this article is the development of a novel approach to construct multifunctional composite scaffolds for bone tissue engineering. For this purpose, different kinds of mineral macroporous supports, water‐soluble aldehyde‐containing copolymers of N‐vinylpyrrolidone, as well as different nonspecific and biospecific ligands governing cell adhesion and growth have been used. The composite materials were tested initially for cytotoxicity in cell culture experiments using a model cell line. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res, 2005