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Effect of hydroxyapatite coating crystallinity on dissolution and osseointegration in vivo
Author(s) -
Xue Weichang,
Liu Xuanyong,
Zheng Xuebin,
Ding Chuanxian
Publication year - 2005
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.30323
Subject(s) - materials science , coating , osseointegration , apatite , crystallinity , dissolution , scanning electron microscope , composite material , biomedical engineering , layer (electronics) , chemical engineering , implant , medicine , surgery , engineering
Hydroxyapatite (HA) coating with different crystallinities were deposited by plasma spraying and vapor‐flame treatment process. Their crystallinities are about 55 and 98%, respectively. These coatings were implanted in cortical bone, muscle, and marrow of dogs. The dissolution and osseointegration behavior were evaluated by scanning electron microscope (SEM) observation histological analysis. The results obtained indicated that after implanted in muscle, a bone‐like apatite layer was formed on the surface of as‐sprayed coating, which was not observed on the surface of the treated coating. The as‐sprayed coating has the ability to induce new bone formation on its surface after implanted in marrow. In contrast, the treated coating displays a limited bone bioactivity. The vapor‐flame process diminishes the short‐term osseointegration properties of the HA coating, but no significant affection was found after three months implantation. Either in muscle or in cortical bone, treated coating exhibits higher stability than the as‐sprayed coating, in some conditions. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res, 2005