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Bioinspired organic‐inorganic composite materials prepared by an alternate soaking process as a tissue reconstitution matrix
Author(s) -
Ogomi Daisuke,
Serizawa Takeshi,
Akashi Mitsuru
Publication year - 2003
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.20053
Subject(s) - materials science , apatite , composite number , polymer , scanning electron microscope , chemical engineering , compatibility (geochemistry) , acrylic acid , composite material , calcium carbonate , calcium , matrix (chemical analysis) , copolymer , metallurgy , engineering
Poly(acrylic acid) (PAAc) grafted poly(ethylene) (PE) (PAAc‐g‐PE) film‐apatite or calcium carbonate (CaCO 3 ) composite materials were prepared by an alternate soaking process, which simply forms apatite or CaCO 3 on the polymer materials by alternate soaking in Ca 2+ ‐ and PO 3− 4 ‐ or CO 3 2− ‐containing solutions. X‐ray diffraction analysis of the composite films indicated the presence of hydroxyapatite or CaCO 3 on the film. Scanning electron microscopic observation revealed that the whole surface of the film was covered by the apatite or CaCO 3 . Cell compatibility tests of the apatite‐ or CaCO 3 ‐coated film suggested that the greater number of cells adhered on the films and that the cell proliferation properties were extremely greater on the films. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res 67A: 1360–1366, 2003