Native extracellular matrix coating on Ti surfaces | Zendy

Pham Minh T. | Zendy; Reuther Helfried | Zendy; Maitz Manfred F. | Zendy

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Native extracellular matrix coating on Ti surfaces

Author(s) -

Pham Minh T.,

Reuther Helfried,

Maitz Manfred F.

Publication year - 2003

Publication title -

journal of biomedical materials research part a

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.849

H-Index - 150

eISSN - 1552-4965

pISSN - 1549-3296

DOI - 10.1002/jbm.a.10575

Subject(s) - fibronectin , extracellular matrix , materials science , titanium , osteoblast , matrix (chemical analysis) , coating , extracellular , fibronectins , biophysics , biomedical engineering , nanotechnology , microbiology and biotechnology , composite material , biochemistry , chemistry , metallurgy , biology , in vitro , medicine

Osteoblast‐like SAOS‐2 cells were allowed to synthesize and assemble their extracellular matrix (ECM) on titanium surfaces. After the selective removal of cells, Ti coated with a native ECM was obtained (ECM‐Ti). The responses of SAOS‐2 cells to ECM−Ti compared with those to peptide sequence RGDS‐ or fibronectin‐immobilized Ti were examined, demonstrating the compositional and structural effects needed to trigger the native cell behavior. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res 66A: 310–316, 2003

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