Premium
Native extracellular matrix coating on Ti surfaces
Author(s) -
Pham Minh T.,
Reuther Helfried,
Maitz Manfred F.
Publication year - 2003
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.10575
Subject(s) - fibronectin , extracellular matrix , materials science , titanium , osteoblast , matrix (chemical analysis) , coating , extracellular , fibronectins , biophysics , biomedical engineering , nanotechnology , microbiology and biotechnology , composite material , biochemistry , chemistry , metallurgy , biology , in vitro , medicine
Abstract Osteoblast‐like SAOS‐2 cells were allowed to synthesize and assemble their extracellular matrix (ECM) on titanium surfaces. After the selective removal of cells, Ti coated with a native ECM was obtained (ECM‐Ti). The responses of SAOS‐2 cells to ECM−Ti compared with those to peptide sequence RGDS‐ or fibronectin‐immobilized Ti were examined, demonstrating the compositional and structural effects needed to trigger the native cell behavior. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res 66A: 310–316, 2003