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Lymph vessels visualization from optical coherence tomography data using depth‐resolved attenuation coefficient calculation
Author(s) -
Moiseev Alexander A.,
Sirotkina Marina A.,
Potapov Arseny L.,
Matveev Lev A.,
Vagapova Nailya N.,
Kuznetsova Irina A.,
Gladkova Natalia D.
Publication year - 2021
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.202100055
Subject(s) - visualization , optical coherence tomography , hessian matrix , lymphatic system , tomography , thresholding , attenuation coefficient , attenuation , partial volume , artificial intelligence , computer science , computer vision , biomedical engineering , optics , physics , mathematics , medicine , pathology , image (mathematics)
Multimodal optical coherent tomography grows popularity with researchers and clinicians over the past decade. One of the modalities is lymphangiography, which allows visualization of the lymphatic vessel networks within optical coherence tomography (OCT) imaging volume. In the present study, it is shown that lymphatic vessel visualization obtained from the depth‐resolved attenuation coefficient distributions, corrected for the noise, shows improved contrast and detail in comparison with previously proposed approaches. We also argue that the two most popular approaches for lymphatic vessel visualization, namely simple intensity thresholding and vesselness calculation based on local Hessian matrix eigenvalues, imply different definitions of the lymphatic vessel's appearance in the OCT volume and lead to the different networks.