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Inside Cover: Localization of PD‐L1 on single cancer cells by iSERS microscopy with Au/Au core/satellite nanoparticles (J. Biophotonics 3/2020)
Author(s) -
Stepula Elzbieta,
König Matthias,
Wang XinPing,
Levermann Janina,
Schimming Tobias,
KasimirBauer Sabine,
Schilling Bastian,
Schlücker Sebastian
Publication year - 2020
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.202070007
Subject(s) - biophotonics , microscopy , cancer cell , raman scattering , raman spectroscopy , nanotechnology , materials science , chemistry , biophysics , cancer , photonics , optics , biology , physics , optoelectronics , genetics
iSERS (SERS=surface‐enhanced Raman scattering) microscopy is an emerging Raman‐based staining technique for the selective localization of target proteins on cells and tissues using antibody‐ SERS nanotag conjugates. In this contribution we demonstrate the feasibility of iSERS for imaging of programmed cell death‐ligand 1 (PD‐L1), an important predictive biomarker, on single SkBr‐3 breast cancer cells. Further details can be found in the article by Elzbieta Stepula, Matthias König, Xin‐Ping Wang, et al. ( e201960034 ).