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Joint time‐frequency analysis of visible laser reflections in a sheep heart
Author(s) -
Stringer Bradley J.,
Shumway Spencer B.,
Willden Jeremy P.,
Kuck Kai
Publication year - 2021
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.202000464
Subject(s) - superior vena cava , fluoroscopy , catheter , right atrium , atrium (architecture) , medicine , laser , vena cava , biomedical engineering , laser diode , cardiology , optics , surgery , atrial fibrillation , physics
Limited methods exist to confirm the position of cardiovascular devices in the superior vena cava or right atrium of the heart. The aim of this study was to design, test and validate the feasibility of whether an optical fiber‐based instrument could accurately distinguish when a cardiovascular catheter was located in the superior vena cava vs in the right atrium. An optical fiber was placed in a cardiovascular catheter which was inserted into a living sheep and guided to the vicinity of the heart where diode laser‐based reflection intensity data were simultaneously gathered from two visible wavelengths of light reflected from the venous and atrial tissue surfaces near the cavoatrial junction. The time series data were postoperatively analyzed using methods of joint time‐frequency analysis and validated against catheter positions determined with fluoroscopy and ECG. The system was successful in distinguishing the location of the superior vena cava from the right atrium.