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Determination and correction of aberrations in full field optical coherence tomography using phase gradient autofocus by maximizing the likelihood function
Author(s) -
Matkivsky Vasily,
Moiseev Alexander,
Shilyagin Pavel,
Rodionov Alexander,
Spahr Hendrik,
Pfäffle Clara,
Hüttmann Gereon,
Hillmann Dierck,
Gelikonov Grigory
Publication year - 2020
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.202000112
Subject(s) - optical coherence tomography , autofocus , optics , physics , strehl ratio , adaptive optics , computer science , focus (optics)
A method for numerical estimation and correction of aberrations of the eye in fundus imaging with optical coherence tomography (OCT) is presented. Aberrations are determined statistically by using the estimate based on likelihood function maximization. The method can be considered as an extension of the phase gradient autofocusing algorithm in synthetic aperture radar imaging to 2D optical aberration correction. The efficacy of the proposed method has been demonstrated in OCT fundus imaging with 6 λ aberrations. After correction, single photoreceptors were resolved. It is also shown that wave front distortions with high spatial frequencies can be determined and corrected.