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Sialolithiasis: Application parameters for an optimal laser therapy
Author(s) -
Faklaris Ioannis,
Bouropoulos Nikolaos,
Vainos Nikolaos A.
Publication year - 2020
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.202000044
Subject(s) - laser , ablation , materials science , ablative case , fragmentation (computing) , pulse duration , power density , irradiation , laser ablation , biomedical engineering , optics , radiation therapy , power (physics) , surgery , medicine , physics , quantum mechanics , computer science , nuclear physics , operating system
In‐vitro experimental parametric studies of laser ablation using natural sialoliths and artificial stones have been performed toward an efficient laser treatment of sialolithiasis. Surface microstructure and water adsorption become critical for coupling high power pulsed Ho:YAG laser radiation ( λ = 2080 nm, τ ∼250 μsec), inducing ablative interactions and stone fragmentation. Results reveal a generic trend, with single pulse laser energy density threshold for sialolith ablative erosion at ∼200 J cm −2 (corresponding to intensity ∼800 kW cm −2 ) and fragmentation rates reaching ∼1 mm/pulse at ∼2400 J cm −2 . This process shows no saturation, suggesting that very high energy density irradiation at low pulse repetition rate is an efficient approach. Such operation facilitates rapid cooling and minimal thermal loading of the oral and maxillofacial area, thus causing negligible adverse effects. The method is expected to contribute to the establishment of an easy and optimal therapeutic protocol for sialolithiasis pathology.