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Front Cover: In vivo detection of endotracheal tube biofilms in intubated critical care patients using catheter‐based optical coherence tomography (J. Biophotonics 5/2019)
Publication year - 2019
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201970011
Subject(s) - endotracheal tube , optical coherence tomography , catheter , ventilator associated pneumonia , biofilm , medicine , ex vivo , in vivo , biomedical engineering , pneumonia , radiology , materials science , anesthesia , intubation , biology , microbiology and biotechnology , genetics , bacteria
A catheter‐based OCT system is used in intubated mechanically‐ventilated critical care patients for the in vivo detection of endotracheal tube biofilm formation, which has been linked to ventilator‐associated pneumonia and death. The combination of attenuation coefficient and structural imaging enables longitudinal monitoring of biofilm growth and differentiation from mucus. In contrast to conventional diagnostic procedures, this approach provides effective real‐time bed‐side detection of biofilms. Further details can be found in the article by Roshan Dsouza, Darold R. Spillman Jr., Ronit Barkalifa, et al. ( e201800307 ).