Premium
Inside Front Cover: Triphenylphosphonium cation: A valuable functional group for antimicrobial photodynamic therapy (J. Biophotonics 10/2018)
Author(s) -
BresolíObach Roger,
Gispert Ignacio,
Peña Diego G.,
Boga Sonia,
Gulias Óscar,
Agut Montserrat,
Vázquez M. Eugenio,
ll Santi
Publication year - 2018
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201870162
Subject(s) - front cover , antimicrobial , perylene , photodynamic therapy , biophotonics , chemistry , cover (algebra) , combinatorial chemistry , nanotechnology , materials science , organic chemistry , photonics , engineering , optoelectronics , molecule , mechanical engineering
The use of light‐activated triphenylphosphonium‐based antimicrobials to tackle the emerging problem of antimicrobial resistance has been proposed in this study. Chemical modification of phenalenone and perylene with triphenylphosphonium cations enhances their photoantimicrobial activity up to 10 7 times. Selective targeting of Gram‐positive bacteria is demonstrated. Further details can be found in the article by Roger Bresolí‐Obach, Ignacio Gispert and Diego García Peña et al. ( e201800054 ). Cover art by M. Eugenio Vázquez, @ChemBioUSC