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Front Cover: Photoacoustic microscopy for evaluating combretastatin A4 phosphate induced vascular disruption in orthotopic glioma (J. Biophotonics 10/2018)
Author(s) -
Bi Renzhe,
Balasundaram Ghayathri,
Jeon Seungwan,
Tay Hui Chien,
Pu Yang,
Li Xiuting,
Moothanchery Mohesh,
Kim Chulhong,
Olivo Malini
Publication year - 2018
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201870161
Subject(s) - photoacoustic imaging in biomedicine , biophotonics , combretastatin , glioma , pathology , skull , medicine , front cover , stroma , biomedical engineering , chemistry , materials science , cancer research , biology , anatomy , cover (algebra) , optics , microbiology and biotechnology , immunohistochemistry , microtubule , photonics , mechanical engineering , physics , optoelectronics , engineering , tubulin
Optical resolution photoacoustic microscopy (OR‐PAM) imaging system is exploited to evaluate the vascular disruptive effect of Combretastatin A4 Phosphate (CA4P), a solid tumor drug, on a murine orthotopic glioma with intact skull. Hemodynamic changes in tumor vasculature are in agreement with the well documented shutdown and recovery associated CA4P administration. High resolution vasculature images obtained using OR‐PAM enable mapping of each individual blood vessel's response to the treatment. Further details can be found in the article by Renzhe Bi, Ghayathri Balasundaram, Seungwan Jeon, et al. ( e201700327 )