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Front Cover: Dual‐wavelength hybrid optoacoustic‐ultrasound biomicroscopy for functional imaging of large‐scale cerebral vascular networks (J. Biophotonics 9/2018)
Author(s) -
Rebling Johannes,
Estrada Héctor,
Gottschalk Sven,
Sela Gali,
Zwack Michael,
Wissmeyer Georg,
Ntziachristos Vasilis,
Razansky Daniel
Publication year - 2018
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201870156
Subject(s) - ultrasound biomicroscopy , biomedical engineering , ultrasound , biophotonics , microscope , microscopy , neuroimaging , medicine , materials science , optics , laser , radiology , pathology , physics , psychiatry
We present a hybrid dual‐wavelength optoacoustic and ultrasound bio‐microscope capable of rapid transcranial visualization of morphology and oxygenation status of large‐scale cerebral vascular networks. Imaging of entire cortical vasculature in mice is achieved with single capillary resolution and complemented by simultaneously acquired pulse‐echo ultrasound microscopy scans of the mouse skull. The new approach holds potential to facilitate studies into neurological and vascular abnormalities of the brain. Further details can be found in the article by Johannes Rebling, Héctor Estrada, Sven Gottschalk, et al. ( e201800057 ).