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Inside Back Cover: Sensitive Leptospira DNA detection using tapered optical fiber sensor (J. Biophotonics 8/2018)
Author(s) -
Zainuddin Nurul H.,
Chee Hui Y.,
Ahmad Muhammad Z.,
Mahdi Mohd A.,
Abu Bakar Muhammad H.,
Yaacob Mohd H.
Publication year - 2018
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201870153
Subject(s) - biophotonics , leptospira , optics , materials science , fiber , optoelectronics , leptospirosis , physics , biology , photonics , virology , composite material
The background microscopic image shows leptospira interrogans bacteria, the source of Leptospirosis, a deadly disease but with common early flu‐like symptoms and likely leads to under‐diagnosed. Highly sensitive leptospira DNA sensor is developed using tapered optical fiber as shown by the schematic image. Laser transmits in the optical fiber interacts with the functionalized amine and aldehyde coatings (bottom images) to produce wavelength shifts upon DNA exposure around the tapered region. Further details can be found in the article by Nurul H. Zainuddin, Hui Y. Chee, Muhammad Z. Ahmad et al. ( e201700363 ).