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Front Cover: Photodynamic opening of the blood‐brain barrier and pathways of brain clearing (J. Biophotonics 8/2018)
Author(s) -
SemyachkinaGlushkovskaya Oxana,
Chehonin Vladimir,
Borisova Ekaterina,
Fedosov Ivan,
Namykin Anton,
Abdurashitov Arkady,
Shirokov Alexander,
Khlebtsov Boris,
Lyubun Yelena,
Navolokin Nikita,
Ulanova Mariya,
Shushunova Natalia,
Khorovodov Alexander,
Agranovich Ilana,
Bodrova Anastasia,
Sagatova Madina,
Shareef Ali Esmat,
Saranceva Elena,
Iskra Tatyana,
Dvoryatkina Mariya,
Zhinchenko Ekaterina,
Sindeeva Olga,
Tuchin Valery,
Kurths Jurgen
Publication year - 2018
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201870151
Subject(s) - superior sagittal sinus , evans blue , parenchyma , blood–brain barrier , pathology , dextran , medicine , photodynamic therapy , chemistry , central nervous system , chromatography , organic chemistry , thrombosis
Fluorescent microscopy of the brain clearing from the FITC‐dextran (red color) via the meningeal lymphatic vessels (green color, labelled by specific antibodies LYVE‐1 conjugated with Alexa 488). The FITC‐dextran injected intravenously immediately is observed in the Sagittal sinus (the main cerebral vein) and after photodynamic opening of blood‐brain barrier it is also presented in the meningeal lymphatic vessels due to activation of brain clearing from accumulated the FITC‐dextran in the brain parenchyma. Further details can be found in the article by Oxana Semyachkina‐Glushkovskaya, Vladimir Chehonin, Ekaterina Borisova, et al. ( e201700287 )