Premium
Front Cover: Assessment of trans‐scleral iontophoresis delivery of lutein to the human retina (J. Biophotonics 3/2018)
Author(s) -
Lombardo Marco,
Villari Valentina,
Micali Norberto,
Roy Pierre,
Sousa Sara H.,
Lombardo Giuseppe
Publication year - 2018
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201870132
Subject(s) - sclera , lutein , iontophoresis , retina , choroid , biophotonics , ophthalmology , human eye , medicine , chemistry , materials science , biology , optics , carotenoid , neuroscience , physics , optoelectronics , biochemistry , radiology , photonics
Trans‐scleral iontophoresis device was shown to be effective for in‐situ delivery of lutein to the retina of human donor eyes. After treatment, Resonance Raman Spectroscopy measurements demonstrated that lutein greatly enriched the inner sclera, choroid and retina. Clinical studies are going to prove if the methodology would be a valuable approach to enrich the human macular pigment and prevent local oxidative damage in patients at risk of AMD progression. Further details can be found in the article by Marco Lombardo et al. ( e201700095 ).