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Front Cover: A high‐throughput all‐optical laser‐scanning imaging flow cytometer with biomolecular specificity and subcellular resolution (J. Biophotonics 2/2018)
Author(s) -
Yan Wenwei,
Wu Jianglai,
Wong Kenneth K. Y.,
Tsia Kevin K.
Publication year - 2018
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201870128
Subject(s) - biophotonics , throughput , high resolution , nanotechnology , ultrashort pulse , visualization , laser , optics , characterization (materials science) , materials science , computer science , artificial intelligence , physics , remote sensing , telecommunications , wireless , geology
A new type of high‐throughput imaging flow cytometer (>20 000 cells s ‐1 ) based upon an all‐optical ultrafast laser‐scanning imaging technique, called free‐space angular‐chirp‐enhanced delay (FACED) is reported. FACED imaging flow cytometers enables high‐throughput visualization of functional morphology of individual cells with subcellular resolution. It critically empowers largescale and deep characterization of single cells and their heterogeneity with high statistical power— an ability to become increasingly critical in single‐cell analysis adopted in a wide range of biomedical and life‐science applications. Further details can be found in the article by Wenwei Yan et al. ( e201700178 )