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Origin of improved depth penetration in dual‐axis optical coherence tomography: a Monte Carlo study
Author(s) -
Zhao Yang,
Chu Kengyeh K.,
Jelly Evan T.,
Wax Adam
Publication year - 2019
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201800383
Subject(s) - optical coherence tomography , optics , monte carlo method , photon , offset (computer science) , physics , tomography , penetration depth , optical axis , coherence (philosophical gambling strategy) , materials science , computer science , statistics , mathematics , lens (geology) , quantum mechanics , programming language
Recent studies have demonstrated that extended imaging depth can be achieved using dual‐axis optical coherence tomography (DA‐OCT). By illuminating and collecting at an oblique angle, multiple forward scattered photons from large probing depths are preferentially detected. However, the mechanism behind the enhancement of imaging depth needs further illumination. Here, the signal of a DA‐OCT system is studied using a Monte Carlo simulation. We modeled light transport in tissue and recorded the spatial and angular distribution of photons exiting the tissue surface. Results indicate that the spatial separation and offset angle created by the non‐telecentric scanning configuration promote the collection of more deeply propagating photons than conventional on‐axis OCT.

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