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Inside Cover: A method to study the hemodynamics of chicken embryo's aortic arches using optical coherence tomography (J. Biophotonics 3/2017)
Publication year - 2017
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201770031
Subject(s) - aortic arch , optical coherence tomography , hemodynamics , anatomy , streamlines, streaklines, and pathlines , blood flow , computational fluid dynamics , biomedical engineering , medicine , physics , aorta , cardiology , radiology , mechanics
It has been understood that hemodynamics could affect the morphological development of the internal organs, which could shed light on congenital cardiovascular defects. Imaging modalities such as ultrasound, corrosion casting and micro‐computed tomography are either invasive or limited in resolution. In this study, high‐resolution OCT and computational fluid dynamics (CFD) are combined to provide quantitative analysis of the embryonic flow mechanics and the associated anatomy in a small animal model. The top left image shows a representative raw OCT image of the chicken embryo cardiac tissues, the top right the OCT image after moving average filtering. The bottom images show CFD simulated blood flow streamlines in aortic arches of the chicken embryo, front view (left) and back view (right). Further details can be found in the article by Zhen Yu Gordon Ko et al. on pp. 353–359.