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Two optical coherence tomography systems detect topical gold nanoshells in hair follicles, sweat ducts and measure epidermis
Author(s) -
Mogensen Mette,
Bojesen Sophie,
Israelsen Niels M.,
Maria Michael,
Jensen Mikkel,
Podoleanu Adrian,
Bang Ole,
Haedersdal Merete
Publication year - 2018
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201700348
Subject(s) - optical coherence tomography , sweat , hair follicle , penetration (warfare) , medicine , biomedical engineering , ophthalmology , operations research , engineering
This study provides novel data on gold nanoshells (GNSs) used as contrast agent in 2 optical coherence tomography (OCT) systems. GNS topically applied and massaged into skin generating increased signals from natural skin openings. This study suggests that GNS is an interesting candidate for increasing sensitivity in OCT diagnosis of hair and sweat gland disorders and has potential for topical drug delivery and that choice of OCT systems matters.