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Trimodal system for in vivo skin cancer screening with combined optical coherence tomography‐Raman and colocalized optoacoustic measurements
Author(s) -
Varkentin Arthur,
Mazurenka Mikhail,
Blumenröther Elias,
Behrendt Lea,
Emmert Steffen,
Morgner Uwe,
MeinhardtWollweber Merve,
Rahlves Maik,
Roth Bernhard
Publication year - 2018
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201700288
Subject(s) - optical coherence tomography , materials science , biomedical engineering , raman spectroscopy , optics , in vivo , medicine , radiology , microbiology and biotechnology , biology , physics
Optical coherence tomography (OCT) has evolved to a powerful tool for medical applications. Yet, often there are insurmountable limits, like the penetration depth of OCT, arising from physical properties of this measurement technique. In other cases, additional information is required or would be helpful to allow robust, pathologically relevant conclusions. Therefore, a multimodal system for thickness assessment of lesions and, in particular, melanoma was developed, combining OCT, optoacoustics and (resonance) Raman spectroscopy.