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Effect of photodynamic therapy for the treatment of halitosis in adolescents – a controlled, microbiological, clinical trial
Author(s) -
Costa da Mota Ana Carolina,
França Cristiane Miranda,
Prates Renato,
Deana Alessandro Melo,
Costa Santos Larissa,
Lopes Garcia Rubia,
Leal Gonçalves Marcela Letícia,
Mesquita Ferrari Raquel Agnelli,
Porta Santos Fernandes Kristianne,
Kalil Bussadori Sandra
Publication year - 2016
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201600067
Subject(s) - photodynamic therapy , tongue , medicine , statistical significance , clinical trial , dentistry , analysis of variance , significant difference , statistical analysis , clinical significance , scraper site , gastroenterology , pathology , chemistry , statistics , mathematics , organic chemistry , mechanical engineering , engineering
Halitosis can exert a negative influence on the social relations of adolescents and affect one's self‐image. The aim of this study was to evaluate the clinical and microbiological effect of antimicrobial photodynamic therapy (aPDT) on halitosis in adolescents. Forty‐six individuals aged 12 to 19 years were randomly allocated: Group 1 – treatment with photodynamic therapy; Group 2 – treatment with a tongue scraper and Group 3 – treatment with a tongue scraper and photodynamic therapy. The count of bacterial colony‐forming units per milliliter was used for the microbiological analysis. Statistical analysis involved the Kruskal–Wallis test followed by the Student–Newman–Keuls test. ANOVA was used for the determination of colony‐forming units after treatment. The level of significance for all statistical tests was 5% ( p < 0.05). After treatment, a statistically significant reduction in total volatile sulfur compounds was found in all groups ( p < 0.001), with the largest reduction (median: 0) found in Group 3 (tongue scraper and photodynamic therapy). Moreover, a statistically significant difference was found between treatment with aPDT and a tongue scraper alone ( p < 0.001). The present findings demonstrate an option for the treatment of halitosis in adolescents, with an immediate effect and without the mechanical aggression to the toungue.Clinical Trials: NCT02007993