Premium
Investigation of the differentiation of ex vivo nerve and fat tissues using laser‐induced breakdown spectroscopy (LIBS): Prospects for tissue‐specific laser surgery
Author(s) -
Mehari Fanuel,
Rohde Maximillian,
Kanawade Rajesh,
Knipfer Christian,
Adler Werner,
Klämpfl Florian,
Stelzle Florian,
Schmidt Michael
Publication year - 2016
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201500256
Subject(s) - laser , ablation , laser ablation , ex vivo , in vivo , context (archaeology) , biomedical engineering , laser induced breakdown spectroscopy , plasma , materials science , spectroscopy , chemistry , optics , medicine , biology , paleontology , physics , microbiology and biotechnology , quantum mechanics
In the present study, the elemental compositions of fat and nerve tissue during their plasma mediated laser ablation are studied in the context of tissue differentiation for laser surgery applications by using Laser‐Induced Breakdown Spectroscopy (LIBS). Tissue samples of porcine fat and nerve were prepared as ex vivo experimental objects. Plasma mediated laser ablation is performed using an Nd : YAG laser in open air and under normal stray light conditions. The performed measurements suggest that the two tissue types show a high similarity in terms of qualitative elemental composition while at the same time revealing a distinct difference in the concentration of the constituent elements. Different analysis approaches are evaluated and discussed to optimize the tissue‐differentiation performance of the LIBS approach.Plasma mediated laser tissue ablation.