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High precision mapping of kidney stones using μ‐IR spectroscopy to determine urinary lithogenesis
Author(s) -
Blanco Francisco,
OrtizAlías Pilar,
LópezMesas Montserrat,
Valiente Manuel
Publication year - 2015
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201300201
Subject(s) - kidney stones , calcium oxalate , apatite , oxalate , urinary system , chemistry , synchrotron , carbonate , mineralogy , urology , medicine , anatomy , inorganic chemistry , physics , organic chemistry , nuclear physics
Evolution of urinary lithiasis is determined by the metabolism and life‐style of the related patient. The appropriate classification of the stone is mandatory for the identification of the lithogenic process. In this study, cros‐sections from a single stone of each of the most frequent urolithiasis types (calcium oxalate mono and dihydrate and carbonate apatite) have been selected and imaged using IR microspectroscopy. Moreover, the use of high definition sFTIR (synchrotron source) has revealed hidden information to the conventional FTIR. This work has demonstrated that minor components become key factors on the description of the stages of stone formation.Intensity map for COM (1630 cm –1 peak). The high spatial definition achieved is key for the precise description of the kidney stone history.