Premium
Laser‐activated adhesive films for sutureless median nerve anastomosis
Author(s) -
Barton Mathew,
Morley John W.,
Stoodley Marcus A.,
Ng KhengSeong,
Piller Sabine C.,
Duong Hong,
Mawad Damia,
Mahns David A.,
Lauto Antonio
Publication year - 2013
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201300054
Subject(s) - anastomosis , adhesive , laser , in vivo , histology , surgery , electrophysiology , surgical anastomosis , rose bengal , medicine , anatomy , biomedical engineering , materials science , chemistry , pathology , biology , optics , composite material , physics , microbiology and biotechnology , organic chemistry , layer (electronics)
A novel chitosan adhesive film that incorporates the dye ‘Rose Bengal’ (RB) was used in conjunction with a green laser to repair transected rat median nerves in vivo . Histology and electrophysiological recording assessed the impact of the laser‐adhesive technique on nerves. One week post‐operatively, the sham‐control group (laser‐adhesive technique applied on un‐transected nerves) conserved the average number and size of myelinated fibres in comparison to its contralateral side and electrophysiological recordings demonstrated no significant difference with un‐operated nerves. Twelve weeks after the laser‐adhesive anastomoses, nerves were in continuity with regenerated axons that crossed the anastomotic site. (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)