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Radiation pressure on a biconcave human Red Blood Cell and the resulting deformation in a pair of parallel optical traps
Author(s) -
Liao GuanBo,
Chen YinQuan,
Bareil Paul B.,
Sheng Yunlong,
Chiou Arthur,
Chang MingShien
Publication year - 2014
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201300017
Subject(s) - elasticity (physics) , wavefront , optics , materials science , optical tweezers , stress (linguistics) , elastic modulus , deformation (meteorology) , gaussian beam , total internal reflection , mechanics , physics , beam (structure) , composite material , linguistics , philosophy
We calculated the three‐dimensional optical stress distribution and the resulting deformation on a biconcave human red blood cell (RBC) in a pair of parallel optical trap. We assumed a Gaussian intensity distribution with a spherical wavefront for each trapping beam and calculated the optical stress from the momentum transfer associated with the reflection and refraction of the incident photons at each interface. The RBC was modelled as a biconcave thin elastic membrane with uniform elasticity and a uniform thickness of 0.25 μm. The resulting cell deformation was determined from the optical stress distribution by finite element software, Comsol Structure Mechanics Module, with Young's modulus ( E ) as a fitting parameter in order to fit the theoretical results for cell elongation to our experimental data. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)