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Back Cover: J. Biophotonics 10/2012
Publication year - 2012
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201290016
Subject(s) - ionotropic effect , photostimulation , excitatory postsynaptic potential , neuroscience , biophysics , glutamate receptor , neuron , chemistry , neurotransmitter , biophotonics , biology , physics , receptor , biochemistry , optics , photonics , central nervous system
Abstract The cover art shows simultaneous multi‐site two‐photon photostimulation along the three‐dimensional (3D) dendritic arbor of a layer II neocortical neuron. Three foci positioned at different planes are shown at which glutamate (Glu) is locally released from its chemical cage (MNI) within each focus. Binding of this neurotransmitter to ionotropic ligand‐gated ion‐channels causes an excitatory post‐synaptic current flow of Na + /Ca ++ into the neuron. Photostimulating synapses at multiple 3D sites could elucidate how neurons process information. (Picture: M. A. Go et al., pp. 101–118 in this issue)