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Cover Picture: J. Biophotonics 8–9/2012
Publication year - 2012
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201290011
Subject(s) - biophotonics , photonics , materials science , photonic crystal , nanotechnology , nanostructure , microscope , nanoimprint lithography , optical microscope , optics , optoelectronics , scanning electron microscope , physics , medicine , alternative medicine , pathology , fabrication , composite material
Abstract Photonic crystal enhanced fluorescence (PCEF) is used to amplify the output from a protein microarray used to detect breast cancer biomarkers. Using nanoimprint lithography, an entire quartz microscope slide is covered with a photonic crystal nanostructure. The photo shows fourteen liquid test samples, containing biomarkers over a range of concentrations, applied as droplets to individual photonic crystals. The goal of this work is to develop a rapid, sensitive, and multiplexed detection of cancer biomarkers within a single droplet of blood. (Picture: B. Cunningham and R. C. Zangar, pp. 617–628, in this issue)