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Resonance Raman based skin carotenoid measurements in newborns and infants
Author(s) -
Ermakov Igor V.,
Ermakova Maia R.,
Bernstein Paul S.,
Chan Gary M.,
Gellermann Werner
Publication year - 2013
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201200195
Subject(s) - carotenoid , raman spectroscopy , medicine , antioxidant , pediatrics , dermatology , chemistry , food science , biochemistry , physics , optics
We describe Resonance Raman based skin carotenoid measurements in newborns and infants. Skin‐ and serum carotenoid levels correlate with high statistical significance in healthy newborns and infants, and with reduced accuracy also in prematurely born infants, who in general feature very low carotenoid levels and thin transparent skin giving rise to large background absorption effects. Skin carotenoid levels can be easily compared among subjects and/or tracked in longitudinal studies with the highly molecule‐specific Raman method. It therefore holds promise as a rapid, non‐invasive, carotenoid antioxidant assessment method for newborns and infants in the field of pediatrics. (© 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)