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Correlation of temperature rise and optical coherence tomography characteristics in patient retinal photocoagulation
Author(s) -
Koinzer Stefan,
Schlott Kerstin,
Portz Lea,
Ptaszynski Lars,
Baade Alexander,
Bever Marco,
Saeger Mark,
Caliebe Amke,
Denner Renè,
Birngruber Reginald,
Brinkmann Ralf,
Roider Johann
Publication year - 2012
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201200091
Subject(s) - optical coherence tomography , retinal , laser , fundus (uterus) , ophthalmology , lesion , medicine , optics , materials science , nuclear medicine , pathology , physics
We conducted a study to correlate the retinal temperature rise during photocoagulation to the afterward detected tissue effect in optical coherence tomography (OCT). 504 photocoagulation lesions were examined in 20 patients. The retinal temperature increase was determined in real‐time during treatment based on thermoelastic tissue expansion which was probed by repetitively applied ns laser pulses. The tissue effect was examined on fundus images and OCT images of individualized lesions. We discerned seven characteristic morphological OCT lesion classes. Their validity was confirmed by increasing visibility and diameters. Mean peak temperatures at the end of irradiation ranged from approx. 60 °C to beyond 100 °C, depending on burn intensity. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)