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Digital imaging in pathology – current applications and challenges
Author(s) -
Brachtel Elena,
Yagi Yukako
Publication year - 2012
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.201100103
Subject(s) - telepathology , virtual microscopy , digital pathology , workflow , medical physics , computer science , modality (human–computer interaction) , digital imaging , visualization , pathology , medicine , multimedia , data science , digital image , image processing , computer vision , artificial intelligence , telemedicine , health care , database , economics , image (mathematics) , economic growth
Conventional histopathology is rapidly shifting towards digital integration. Will microscopes (and pathologists) soon be obsolete? Or are we dealing with just another image modality that leaves the core of tissue diagnosis intact? This article provides an overview of current digital pathology applications and research with emphasis on whole slide imaging (WSI). Static or interactive digital pathology work stations already can be used for many purposes, e.g. telepathology expert consultations, frozen section diagnosis in remote areas, cytology screening, quality assurance, diagnostic validations for clinical trials, quantitation of hormone receptor or HER2 studies in breast cancer, or three‐dimensional visualization of anatomical structures, among others. Changes of workflow in histology laboratories are beginning to enable digital image acquisition and WSI in a routine setting. WSI plays an increasing role in pathology education, glass slide boxes in medical schools are being replaced by digital slide collections; digital slide seminars and virtual microscopy are used for postgraduate and continuing medical education in pathology. Research and efforts to validate WSI systems for diagnostic settings are ongoing. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)