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Application of aluminum phthalocyanine nanoparticles for fluorescent diagnostics in dentistry and skin autotransplantology
Author(s) -
Vasilchenko Sergey Yu.,
Volkova Anna I.,
Ryabova Anastasiya V.,
Loschenov Victor B.,
Konov Vitaly I.,
Mamedov Adil A.,
Kuzmin Sergey G.,
Lukyanets Evgeniy A.
Publication year - 2010
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.200900099
Subject(s) - fluorescence , phthalocyanine , nanoparticle , nanotechnology , aluminium , materials science , dentistry , dermatology , biomedical engineering , medicine , optics , metallurgy , physics
This paper deals with the possibility of application of aluminum phthalocyanine (AlPc) nanoparticles in clinical practice. AlPc fluoresces in the molecular form but in the form of nanoparticles it does not. Separation of molecules from an AlPc nanoparticle and therefore the appearance of fluorescence occurs under the effect of a number of biochemo‐physical factors. Owing to this feature the application of AlPc nanoparticles followed by the measurement of fluorescence spectra is proposed as a diagnostics method. It was shown that after AlPc nanoparticle application on a tooth surface the fluorescence intensity in the enamel microdamage area is 2–3 times higher than that in the normal enamel area. The appearance of fluorescence after application of AlPc nanoparticles on skin autografts testifies to the presence of inflammation. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)