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Polarized diffuse reflectance measurements on cancerous and noncancerous tissues
Author(s) -
Manhas Sandeep,
Swami Mahesh K.,
Patel Hari S.,
Uppal Abha,
Ghosh Nirmalya,
Gupta Pradeep K.
Publication year - 2009
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.200810065
Subject(s) - mueller calculus , polarization (electrochemistry) , human breast , optics , chemistry , linear polarization , oral cavity , reflectivity , polarimetry , materials science , analytical chemistry (journal) , physics , breast cancer , biology , cancer , scattering , medicine , chromatography , dentistry , laser , genetics
We report the measurement of polarization parameters (linear retardance, diattenuation and depolarization) of normal and malignant tissue from human oral cavity and breast over the spectral range 390 nm to 550 nm. These parameters were determined using the 3 × 3 Mueller matrix, the elements of which could be determined using linear polarization measurements only. The significant differences observed in the polarization parameters of the normal and malignant tissues appear to arise because of the changes in the collagen matrix in the two tissue types. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)