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Optical investigations of the RNA polymerase molecular motor
Author(s) -
Strick Terence R.
Publication year - 2008
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.200810030
Subject(s) - molecular motor , polymerase , rna , rna polymerase , computational biology , biology , dna , chemistry , microbiology and biotechnology , nanotechnology , biophysics , genetics , gene , materials science
Molecular motors have been extensively studied over the past 25 years using a range of optical microscopy methods. The specific example of RNA polymerase, responsible for transcribing the information encoded in DNA into RNA, illustrates the strength of the convergence between these recent approaches and the vast store of data collected over the past half century using the more “classical” approaches of genetics, biochemistry, and structure elucidation. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)