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Tracking bio‐molecules in live cells using quantum dots
Author(s) -
Chang YunPei,
Pinaud Fabien,
Antelman Joshua,
Weiss Shimon
Publication year - 2008
Publication title -
journal of biophotonics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.877
H-Index - 66
eISSN - 1864-0648
pISSN - 1864-063X
DOI - 10.1002/jbio.200810029
Subject(s) - quantum dot , tracking (education) , nanotechnology , molecule , optoelectronics , chemistry , physics , materials science , quantum mechanics , psychology , pedagogy
Single particle tracking (SPT) techniques were developed to explore bio‐molecules dynamics in live cells at single molecule sensitivity and nanometer spatial resolution. Recent developments in quantum dots (Qdots) surface coating and bio‐conjugation schemes have made them most suitable probes for live cell applications. Here we review recent advancements in using quantum dots as SPT probes for live cell experiments. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)