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Basis for body weight exponent (0.75) as a scaling factor in energy metabolism and risk assessment
Author(s) -
Sidhu Kirpal S.
Publication year - 1992
Publication title -
journal of applied toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.784
H-Index - 87
eISSN - 1099-1263
pISSN - 0260-437X
DOI - 10.1002/jat.2550120503
Subject(s) - exponent , energy metabolism , scaling , basis (linear algebra) , risk factor , body weight , mathematics , medicine , endocrinology , geometry , philosophy , linguistics
The basis that led to the adoption of the exponent (0.75) as a scaling factor for the relationship between body weight and energy metabolism is presented. In the risk assessment formulation, it may be appropriate to use the 0.75 power of body weight as a scaling factor for carcinogenicity data obtained from animal studies.