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Thallium replaces potassium in activation of the (Na + , K + )‐atpase of rat liver plasma membranes
Author(s) -
Favari Liliana,
Mourelle Marisabel
Publication year - 1985
Publication title -
journal of applied toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.784
H-Index - 87
eISSN - 1099-1263
pISSN - 0260-437X
DOI - 10.1002/jat.2550050106
Subject(s) - membrane , thallium , potassium , chemistry , atpase , radiochemistry , plasma , sodium , nuclear chemistry , inorganic chemistry , biochemistry , enzyme , physics , organic chemistry , quantum mechanics
The capacity of thallium to substitute for K + in activation of (Na + , K + )‐ATPase of liver plasma membranes was studied. Our results indicate that Tl + can replace K + in the activation of the (Na + , K + )‐ATPase of liver plasma membranes. In the presence of Na + , similar activation is obtained with Tl + concentrations only 1/10 of those of K + . In all other aspects, the (Na + , K + )‐ and (Na + , Tl + )‐ATPases were found to be identical.
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