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Identification of 2‐Nitrofluorene in diesel exhaust particulates
Author(s) -
Xu X. B.,
Nachtman J. P.,
Rappaport S. M.,
Wei E. T.,
Lewis S.,
Burlingame A. L.
Publication year - 1981
Publication title -
journal of applied toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.784
H-Index - 87
eISSN - 1099-1263
pISSN - 0260-437X
DOI - 10.1002/jat.2550010312
Subject(s) - chemistry , diesel exhaust , chromatography , gas chromatography , particulates , dichloromethane , ames test , mutagen , mass spectrometry , diesel fuel , environmental chemistry , carcinogen , organic chemistry , solvent , biology , salmonella , bacteria , genetics
Diesel exhaust particulates contain mutagens which are direct‐acting in the Ames test. A dichloromethane extract of these particulates was separated by liquid chromatography and analyzed by high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS). 2‐Nitrofluorene, a known carcinogen and direct mutagen, was positively identified by comaxima of ion fragments and retention time on the gas chromatograph.