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The influence of selenium on mercury distribution in mice after exposure to low dose Hg° vapours
Author(s) -
Hansen Jens C.,
Kristensen Preben,
Westergaard Ingrid
Publication year - 1981
Publication title -
journal of applied toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.784
H-Index - 87
eISSN - 1099-1263
pISSN - 0260-437X
DOI - 10.1002/jat.2550010304
Subject(s) - mercury (programming language) , selenium , chemistry , vapours , tissue distribution , mercure , kidney , environmental chemistry , toxicokinetics , mercury exposure , lung , toxicity , radiochemistry , physiology , endocrinology , medicine , biology , organic chemistry , computer science , biomonitoring , neuroscience , programming language
The influence of selenium administration on retention, elimination and organ distribution of mercury was studied in female mice exposed to 30 or 80 μg m −3 mercury vapour. The results demonstrated that, as after low doses of mercuric mercury, only excess selenium reduced the elimination of retained mercury vapour from the whole body. However, selenium was able to influence the organ distribution of mercury, even when the whole body burden of mercury was not affected. In mice, contrary to rats, selenium increased the lung and kidney concentrations of mercury without affecting its concentration in the liver.