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Chronic studies in rats exposed to liquid effluent from coal gasification process
Author(s) -
Kostial K.,
Blanuša M.,
Rabar I.,
Maljković T.,
Kello D.,
Landeka M.,
Bunarević A.,
Stara J. F.
Publication year - 1981
Publication title -
journal of applied toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.784
H-Index - 87
eISSN - 1099-1263
pISSN - 0260-437X
DOI - 10.1002/jat.2550010103
Subject(s) - effluent , trace element , zoology , excretion , chemistry , coal , chronic toxicity , environmental chemistry , toxicity , biology , medicine , environmental engineering , biochemistry , environmental science , organic chemistry
The health effects of the E‐effluent (water for quenching ash) from a coal gasification plant were assayed in a chronic experiment (16 month exposure) and a three generation reproduction study. Animals exposed to 100% E‐effluent had an increased daily intake of various inorganic elements (Fe, Cu, K, I, Se, Cd, Hg, Pb, As, F and Cr). In spite of that, the exposed and control animals had the same mortality rate, haematological findings, urinary protein excretion, trace element concentrations in kidneys, liver and femur, bone composition and morphometry, and histological findings. The pre‐ and post‐natal development and growth was unchanged during three generations. It is concluded that the higher intake of various inorganics caused no change in the parameters measured.