Open AccessRecent advances in bone marrow stromal cell trans‐plantation to animals with spinal cord injury
Author(s) -
Li TingTing,
Yuan Hao
Publication year - 2019
Publication title -
ibrain
Language(s) - English
Resource type - Journals
eISSN - 2769-2795
pISSN - 2313-1934
DOI - 10.1002/j.2769-2795.2019.tb00033.x
Subject(s) - medicine , stromal cell , spinal cord injury , regeneration (biology) , bone marrow , spinal cord , transplantation , tendon , pathology , surgery , biology , microbiology and biotechnology , psychiatry
As a kind of myeleterosis, spinal cord injury (SCI) could cause crush injury, contusion, hemisection at different degrees. Meanwhile, the transection of the spinal cord could result in severe neurologic dysfunction and disability which bring enormous disadvantages to patients and their families. It is urgent to find out an effective therapy for SCI. Bone marrow stromal cells (BMSCs) derived from bone marrow which are able to differentiate into many cell types to repair numerous tissues, tendon, and cardiac muscle. BMSCs are also been used to support the recovery of light‐damaged retinal and cardiomyocyte regeneration. BMSC transplantation applied to SCI rats has been investigated for many years, but new methods combined with BMSCs transplantation are always on the way. This review was focused on the application of BMSCs in SCI.