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Direction of pion‐induced radioactivity by autoradiography and positron emission tomography
Author(s) -
Shirato Hiroki,
Harrison Robert,
Kornelsen R. O.,
Lam Gabriel K. Y.,
Gaffney Cristopher C.,
Goodman George B.,
Grochowski Ed,
Pate Brian
Publication year - 1989
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1002/j.2473-4209.1989.tb36307.x
Subject(s) - positron emission tomography , pion , dosimetry , positron emission , nuclear medicine , positron , physics , aluminium , materials science , image resolution , nuclear physics , radiochemistry , nuclear magnetic resonance , optics , chemistry , medicine , electron , metallurgy
An autoradiographic technique incorporating a new imaging system was used to detect pioninduced radioactivity in Plexiglass and the results were compared with aluminium activation and PET imaging. The activity distribution in the region of the pion‐stopping peak was similar in all three cases. Another large signal in the entrance region due to in‐flight interactions [ 12 C(π −, π − π) 11 C] was detected by autoradiography and by PET but was not reflected in the aluminium activation measurements. This new technique is capable of defining the stopping region in phantoms with a better resolution than PET scanning and is useful as a complementary technique to other methods of pion dosimetry.