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3.4.3 Genomics: Requirements Going From Art to Industry
Author(s) -
Kosack Daniel
Publication year - 2004
Publication title -
incose international symposium
Language(s) - English
Resource type - Journals
ISSN - 2334-5837
DOI - 10.1002/j.2334-5837.2004.tb00519.x
Subject(s) - genomics , rework , process (computing) , organism , functional genomics , computer science , dna sequencing , data science , genome , biology , genetics , gene , embedded system , operating system
Genomics is a new science that is contributing significantly to our understanding of genes, life processes, and disease. Genomics endeavors to look at the entire organism – the complete DNA ‐ to study its entire gene set, observing mutations and diversity. Producing the entire DNA sequence and identifying the genes within is no easy task. As budgets are cut and cost becomes more important, the role of organized software and systems engineering becomes more pronounced. This paper describes the systems used at the Institute for Genomic Research (TIGR) to produce the sequence of an organism. The paper begins with an overview of the overall Genomics process. It follows with a discussion of the human genome project and how lessons learned from the project regarding scale and capability have affected the Genomics view of systems design. The paper continues with discussion about the need for traceable, consistent requirements and organized system design in Genomics. Finally, the paper discusses how the Institute for Genomic Research recognizes and addresses the need for proper systems development through requirements gathering and analysis, system decomposition, and rework.